The Use of Contrast-Enhanced Sonography for Therapy Monitoring of Metastatic Lymph Nodes: A Systematic Review

Metastatic cervical lymph nodes are a frequent finding in head and neck squamous cell carcinoma (HNSCC). If non-surgical approach is primarily chosen, therapy response evaluation of the primary tumor affected necessary follow-up. Supplementary contrast-enhanced ultrasound (CEUS) can be used to precisely visualize microcirculation target lesion neck, whereby malignant benign findings differ their uptake behavior. The same applies many other solid tumors. For various entities, it has already been shown that monitoring possible through regular sonography or nodes. Thus, some cases, maybe future, change strategy achieved at an early stage case non-response or, success, de-escalation subsequent (surgical) measures achieved. In this paper, systematic review available studies discussion potential by means CEUS HNSCC presented.